What are genetic disorders, syndrome & mutations?
Genetic syndromes and genetic disorders are genetic problems or conditions that occur due to abnormalities in more than one genome. Genetic disorders can be passed from parent to child; hereditary or genetic disorders can result from changes in the individual's DNA or specific mutations. The genes mutated in pancreatic cancer include KRAS2, p16/CDKN2A, TP53, and SMAD4/DPC4. These are accompanied by a substantial compendium of genomic and transcriptomic alterations that facilitate cell cycle deregulation, cell survival, invasion, and metastases. (Sources: science.gov )
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