Jreissati Family Pancreatic Cancer Centre in Collaboration with Royal Melbourne
This project centres on the development of a novel clinical screening tool in people with diabetes and chronic pancreatitis for the early detection of pancreatic cancer.
Early detection of pancreatic cancer using a novel clinical screening tool in people with diabetes and chronic pancreatitis.
2020/21 Early Detection Initiative
Epworth Medical Foundation
Associate Professor Andrew Metz
Time required to complete project
This project centres on the development of a novel clinical screening tool in people with diabetes and chronic pancreatitis for the early detection of pancreatic cancer. This research brings together for the first time the disciplines of gastroenterology and endocrinology to unify their different perspectives of pancreatic disease as well as endocrine and exocrine dysfunction. This project aims to find a correlation between the diagnosis of type 3c diabetes and the onset of pancreatic cancer. The investigators are long term colleagues and have together created an extensive database over 20 years comprising >10,000 patients with diabetes and/or chronic pancreatitis treated at the Royal Melbourne and Epworth Hospitals. Given over 96,000 people are diagnosed with diabetes annually in Australia it would be cost prohibitive to screen all people for pancreatic cancer, however determining diabetes disease subtypes such as classifying with features of type 3c diabetes along with weight categories, age, family history of neoplasia and blood biomarkers, may provide us with a novel and cost-effective screening application. This research is novel and aims to challenge the status quo by altering diagnostic paradigms to improve outcomes for people with pancreatic cancer.
Collaborative led by A/Prof Andrew Metz, Epworth HealthCare, Royal Melbourne Hospital
This project is proudly supported by a collaboration between PanKind, Tour De Cure and Woolworths Limited through Woolies Walks and Wheels.
A/Prof Spiros Fourlanos, Royal Melbourne Hospital
Mr Brett Knowles, St Vincent’s Hospital, Royal Melbourne Hospital, Peter MacCallum Cancer Centre, Epworth HealthCare
Dr Caroline Le, Epworth HealthCare
Funding partners: Tour de Cure and Woolworths Ltd. through Woolies Wheels and Walks
Funding amount: $164,138.00