Professor Des Richardson
Development of Novel Agents that Target P-Glycoprotein Resistant Pancreatic Cancer
Grant
Development of Novel Agents that Target P-Glycoprotein Resistant Pancreatic Cancer
Award
2015 Innovation Grant
Institution
University of Sydney
Principal Investigator
Professor Des Richardson, Professor of Cancer Cell Biology, NHMRC Senior Principal Research Fellow
Time required to complete project
1 year
Project Summary
Drug resistance is a major factor underlying the limited response of pancreatic cancer to chemotherapy. The project team’s drug design strategy is to target resistant pancreatic cancer by taking advantage of detoxifying P-glycoprotein pump to transport our drugs DIRECTLY to their sensitive site of action in the cancer cell (namely, the LYSOSOME).
Professor Des Richardson