Pankind Scientific Meeting 2025 Program

Scientific Meeting 2024 43

Pankind, Pancreatic Cancer Australia, respectfully acknowledges the Gadigal of the Eora  nation as the Traditional Custodians of this land on which we meet today. We would also like to pay our  respects to Elders past, present and emerging.

Welcome from CEO Michelle Stewart

Michelle Stewart

Dear Guests,

On behalf of Pankind, Pancreatic Cancer Australia, it is my great pleasure to welcome you to our 2025 Scientific Meeting.

This year marks an important milestone for Pankind, with $2.5 million invested into pancreatic cancer research, bringing our total research investment to $20.5 million since inception. Research remains our central focus because we know that scientific discovery is the path to improving outcomes and, ultimately, saving lives.

The theme for this year’s meeting  “The Road to Treatment” captures both the momentum and optimism we share. Across Australia and around the world, there is a growing sense of progress as researchers move closer to new treatment options, better detection pathways, and more personalised care. Each contribution from this vibrant scientific community brings us another step forward on that road.

Alongside our research efforts, Pankind provides vital support for people affected by pancreatic cancer. Through our flagship resource “Living with Pancreatic Cancer,” we offer trusted information to help patients and carers navigate diagnosis, treatment and care. Our Support Navigator and partnership with TrialScreen ensure people can access personalised guidance and clinical trial opportunities.

We are proud to fund a surveillance study with the Jreissati Pancreatic Centre at Epworth for those at higher risk, building clarity and structure around early detection. Pankind also advocates for access to genomic profiling and clinical trials.

We are also working to raise awareness in collaboration with the many fantastic organisations dedicated to improving outcomes in pancreatic cancer, because progress is only possible when we move forward together.

Together, these initiatives demonstrate Pankind’s commitment to driving change through world-class research, patient support, and strong collaboration across the pancreatic cancer community.

We are deeply grateful to the scientific community for your passion, persistence and partnership. Your work inspires hope for every person and family affected by this disease.

We look forward to an engaging and inspiring meeting as we continue, together, along the Road to Treatment.

With best wishes,
Michelle Stewart

Chief Executive Officer

Organising Committee

BLEE 2022 (1)

Dr Belinda Lee

MBBS, MRCP (UK), PGDip (Oncology) FRACP

 A/Prof Savio Barretto

A/Prof Savio Barretto

Gastrointestinal and Hepato-Pancreato- Biliary Surgeon, academic and researcher, Flinders University

Prof Anthony Gill

Prof Anthony Gill AM

MBBS MD FRCPA

Our research impact

Since our inception in 2008, we have invested $18 million across 76 high-calibre research projects. These span across 21 different universities and institutions, funding some of Australia’s top research talent.

In 2025, we are investing a record $2.5 million through our grant round - our largest research investment to date.

Find out more about our Research impact

OUR RESEARCH IMPACT

scientific-meeting-audience

2025 Workshop Program

8.30 - 9.00

Arrival and registration

9:00 - 9:10

Welcome and Introductions

9:10 - 10:25

Plenary Session: Global Insights; Advancing Pancreatic Cancer Treatment

Chair: Ross McKinnon

Dr Eileen O'Reilly -Memorial Sloan Kettering Cancer Center, USA
Pancreas Cancer 2025: New and Emerging Therapies


Dr Andrew Lowy -University of California, San Diego, USA
Reimagining Surgery for Pancreatic Cancer

10:25 - 11:10

Morning Tea and Posters

11:10 - 12:00

Session 1: Clinical Impact

Chair: Belinda Lee


Prof David Thomas - Omico
The rapidly evolving therapeutic landscape in pancreatic cancer


Prof Jayesh Desai - Peter MacCallum Cancer Center
Innovative early phase therapies for pancreatic cancer

12:00 - 13:00

Session 2: New Treatments and Targeted Therapies

Chair: George Barretto

Prof Andrew Scott - Olivia Newton John Cancer Research Institute
Targeting the tumour microenvironment in pancreatic cancer

Prof Claudine Bonder - University of South Australia
Reinvigorating anti-tumour immunity to overcome pancreatic ductal adenocarcinoma

Dr Shona Ritchie - Garvan Institute of Medical Research
Identifying PCSK9 as a potential therapeutic co-target in metastatic pancreatic ductal adenocarcinoma

13:00 - 14:00

Lunch break

14:00 - 15:00 

Session 3: Early Detection

Chair: Chris Baggoley


Stellene Vitaro on behalf of Dr Jean Winter - Flinders University
Exploring the plasma proteome to find biomarkers that can detect early-stage pancreatic ductal adenocarcinoma

Dr Ying Zhu - University of Technology Sydney
Single Extracellular Vesicle Analysis: A Promising Liquid Biopsy Approach for the Early Detection of Pancreatic Cancer

Dr Charbel Sandroussi - University of Sydney
Clinical Implications of Early Detection: Insights from a Surgical Perspective

15:00 - 15:40

Panel discussion

Emerging therapies: What's Next and What's Beyond?

Moderator: Steve Robson, Clinician & Surgeon, Author and Leader in Health Policy

Panelists:
Jayesh Desai - Peter MacCallum Cancer Center
Eileen O'Reilly - Memorial Sloan Kettering Cancer Center
Andrew Lowy - University of California, San Diego
Sean Grimmond- University of Melbourne
Charbel Sandroussi- Royal Prince Alfred Hospital

15:40 - 16:00

Afternoon Tea and Posters

16:00 - 16:30

Session 4: Selected Abstracts

Chair: Amber Johns


Diana Schuhmacher - Garvan Institute of Medical Research
CK2 inhibition as a promising treatment for chemotherapy-resistant pancreatic ductal adenocarcinoma


Layla-Rose Lynam - The University of Queensland
Targeting Epigenetic inhibition as a therapeutic for Pancreatic Cancer


Dr David Herrmann - Garvan Institute of Medical Research
Targeting the NPY/NPY1R signaling axis impairs metastasis and tissue wasting in pancreatic cancer

16:30 - 17.05

2025 Grant Announcement

17:05 - 17.15

Closing Remarks and Discussion

17:15 - 19:00

Networking Drinks

All attendees. Blaxland Ballroom, Swissotel

Ask a question

Ask a question

Have a question for our speakers? Please click the button below to send your question through for the Q&A session.

Plenary Session Speakers

We're thrilled to welcome two global leaders to our plenary session: Dr. Eileen O’Reilly from Memorial Sloan Kettering Cancer Center, New York, and Dr. Andrew Lowy from the University of California, San Diego. Both Dr O'Reilly and Dr Lowy are also key members of our Scientific Advisory Panel.

Eileen M. O’Reilly, MD, FASCO

Eileen M. O’Reilly, MD, FASCO

Memorial Sloan Kettering Cancer Center

Andrew Lowy

Andrew Lowy

Professor of Surgery, Chief, Division of Surgical Oncology - Moores Cancer Centre, University of California, San Diego

Session Speakers

David Thomas Omico

Prof. David Thomas

University of New South Wales, Chief Strategy and Science Officer at Omico

Jayesh Desai

Prof. Jayesh Desai

Peter MacCallum Cancer Centre

Prof. Andrew Scott

Prof. Andrew Scott

Olivia Newton-John Cancer Research Institute

Professor Claudine Bonder

Prof. Claudine Bonder PhD

Centre for Cancer Biology

Dr Shona Ritchie

Dr Shona Ritchie PhD

Garvan Institute

Dr Jean Winter

Dr Jean Winter

Flinders University

Dr Ying Zhu

Dr Ying Zhu PhD

University of Technology Sydney

Panel discussion chair

Steve Robson

Steve Robson

Clinician and surgeon, author and leader in health policy

Poster and Oral Abstracts

Targeting Epigenetic inhibition as a therapeutic for Pancreatic Cancer
Principal Investigator: Layla Lynam
Institute: Frazer Institute, University of Queensland

CK2 inhibition as a promising treatment for chemotherapy resistant pancreatic ductal adenocarcinoma
Principal Investigator: Diana Schuhmacher
Institute: Monash University

Targeting the NPY/NPY1R signaling axis impairs metastasis and tissue wasting in pancreatic cancer
Principal Investigator: David Hermann

Single-Section Spatial Transcriptomic and Metabolomic Profiling of the Pancreatic Cancer Microenvironment
Principal Investigator: Jason Lee
Institution: Frazer Institute, University of Queensland

Targeting de novo lipogenesis improves gemcitabine-based chemotherapy efficacy in pancreatic ductal adenocarcinoma
Principal Investigator: Sarah Hancock
Institution: UNSW Sydney, Victor Chang Cardiac Research Institute

Initial perceptions of Australian clinicians participating in the SCANPatient
clinical trial of synoptic reporting of CT scans to assess pancreatic cancer
Principal Investigator: Lin Li
Institution: Monash University

Evaluating reliability of structured computed tomography scan reporting in pancreatic cancer staging: insights from a quality assurance study exploring inter- and intra-observer agreement and variability
Principal Investigator: Ariadna Recasens
Institution: Monash University

Portal venous circulating tumour cells as a biomarker for relapse prediction in resected pancreatic cancer
Principal Investigator: Dannel Yeo
Institution: Centenary Institute, The University of Sydney, Royal Prince Alfred Hospital

Cellular barcoding of pancreatic cancer cells, supports the tracking of metastatic clones
Principal Investigator: Deanna Miller
Institution: Garvan Institute of Medical Research, University of New South Wales

Targeting Copper in combination with standard-of-care chemotherapy reduces fibrosis and metastasis in PDAC
Principal Investigator: Ellie Mok
Institution: The Garvan Institute of Medical Research and the Kinghorn Cancer Centre

Identifying and targeting FOLFIRINOX resistance mechanisms to improve outcomes in pancreatic cancer
Principal Investigator: Katie Gordon
Institution: Garvan Institute of Medical Research and Kinghorn Cancer Centre, St Vincent’s Clinical School

Nanocarriers for pancreatic ductal adenocarcinoma diagnosis and treatment
Principal Investigator: Melissa Stanfield
Institution: RMIT University

Enhancing the efficacy of and overcoming resistance to Kras Inhibitors in Pancreatic Cancer
Principal Investigator: Niamh Mills
Institution: Garvan Institute of Medical Research and The Kinghorn Cancer Centre

The Influence of Mechanically Activated Ion Channels in Pancreatic Cancer
Principal Investigator: Riley Mumberson
Institution: UNSW

ADAM10 promotes pancreatic cancer progression and modulates the immune microenvironment
Principal Investigator: Sakshi Arora
Institution: Olivia Newton-John Cancer Research Institute and La Trobe University

Co-targeting thrombospondin-1 (THBS-1) to improve KRAS inhibitor efficacy in pancreatic cancer
Principal Investigator: Victoria Tyma
Institution: Garvan Institute of Medical Research,, UNSW

Pankind previous grant recipients

2024 Early Detection Innovation Grants

Development of a non-invasive urine screening test to identify patients with early pancreatic cancer (Marianne Allan Pancreatic Cancer Research Grant)
Principal Investigator: Belinda Lee
Institute: Walter and Eliza Hall Institute of Medical Research

Single extracellular vesicle analysis to identify high-risk pancreatic cancer precursor lesions
Principal Investigator: Ying Zhu
Institute: University of Technology Sydney

Exploring the plasma proteome to find biomarkers that can detect early-stage pancreatic ductal adenocarcinoma
Principal Investigator: Jean Winter
Institute: Flinders University

2024  New Treatment Grants

Enhancing the efficacy of and overcoming resistance to Kras Inhibitors in Pancreatic Cancer
Principal Investigator: Kendelle Murphy
Institute: Garvan Institute of Medical Research 

Targeting fibrosis to improve clinical KRAS G12D inhibitor MRTX1133 efficacy in pancreatic cancer
Principal Investigator: Brooke Pereira
Institute: Garvan Institute of Medical Research

Novel radiopharmaceutical therapies targeting tumour stroma for treating pancreatic cancer
Principal Investigator: Andrew Scott
Institute: Olivia Newton-John Cancer Research Institute

Advancing a new targeted antibody to combat pancreatic cancer
Principal Investigator: Claudine Bonder
Institute: University of South Australia

2023 Early Detection Innovation Grant (Marianne Allan Pancreatic Cancer Research Grant)

Development of a blood based test to identify patients with early pancreatic cancer.
Principal Investigator: Dr Belinda Lee
Institute: Walter and Eliza Hall Institute of Medical Research

2023 New Treatment Grants

Receptor-directed precision medicines for pancreatic cancer
Principal Investigator: Prof John Hooper
Institute: Royal Brisbane and Women's Hospital

PemOla: A phase II study combining pembrolizumab and olaparib in metastatic pancreatic adenocarcinoma patients with high tumour mutation burden
Principal Investigator: Dr Daniel Croagh
Institute: Australian Gastro Intestinal Trials Group

Targeting oncogenic Pol-II transcription cycles using cyclin-dependent-kinase inhibitors: a new therapeutic approach for pancreatic cancer
Principal Investigator: Prof Ricky Johnstone
Institute: University of Melbourne

 

Targeting lymph-pancreas interactions to treat pancreatic cancer
Principal Investigator: Dr Enyuan Cao
Institute: Monash University

 

New pancreatic cancer treatment involving Aryl Hydrocarbon Receptor (AhR) inhibition in the tumour and microenvironment
Principal Investigator: A/Prof Jennette Sakoff
Institute: Calvary Mater Newcastle

 

Polymer mimics of the TRAIL protein for pancreatic cancer
Principal Investigator: Dr Robert Chapman
Institute: The University of Newcastle

2022 Early Detection Innovation Grants

Lighting up the needle in the haystack: targeting malignant stroma to detect early pancreatic cancer on PET.
Principal Investigator: A/Prof David Cavallucci
Institute: Royal Brisbane and Women's Hospital

Development of an early detection biomarker for pancreatic cancer.
Principal Investigator: A/Prof Jason Lee
Institute: QIMR Berghofer Medical Research Institute

A blood test for early detection of pancreatic cancer by single extracellular vesicle analysis.
Principal Investigator: Dr Ying Zhu
Institute: University of Technology Sydney

Identifying metabolic changes in pancreatic fibroblasts during development of pancreatic cancer to facilitate early detection.
Principal Investigator: Dr Zaklina Kovacevic
Institute: The University of Sydney

2022 New Treatment Accelerator Grants

Trapping pancreatic cancer in a crossfire: investigating a combination treatment approach designed to eradicate pancreatic cancer.
Principal Investigator: Dr Alex Staudacher and Dr Vasilios Liapis
Institute: Central Adelaide Local Health Network

Targeting epigenetic modifying enzymes as a novel therapy for pancreatic cancer.
Principal Investigator: A/Prof Jason Lee
Institute: QIMR Berghofer Medical Research Institute

Advanced analysis of lipid metabolism in pancreatic cancer to reveal new therapeutic targets
Principal Investigator: Prof Nigel Turner
Institute: Victor Chang Cardiac Research Institute

Using precision medicine approaches in pancreatic cancer to improve chemosensitivity via porcupine inhibition.
Principal Investigator: Dr Sean Porazinski
Institute: Garvan Institute of Medical Research

2021 Early Detection Innovation Grants

1Development of Biomarker Tests for Early Detection/Diagnosis of Pancreatic Cancer.
Principal Investigator: Prof Anubhav Mittal
Institute: The University of Sydney

Advancing a novel ‘early detection’ biomarker for PDAC.
Principal Investigator: Prof Claudine Bonder
Institute: Centre for Cancer Biology

Deciphering the Exosomal RNA Cargo in Pancreatic Cancer-related diabetes using Transcriptmonics: A Novel Approach for Early Detection of Pancreatic Cancer
Principal Investigator: Dr Chamini Perera
Institute: The University of New South Wales

Early Detection and Diagnosis of Pancreatic Cancer using Circulating Tumour Cells.
Principal Investigator: Prof John Rasko
Institute: The University of Sydney

Can the molecules carried by exosomes help to diagnose pancreatic cancer early?
Principal Investigator: Prof Marco Falasca
Institute: Curtin University

2021 New Treatment Accelerator Grants

3D Human Tumour Explant Culture to Inform Precision Medicine in Pancreatic Cancer.
Principal Investigator: Dr George Sharbeen
Institute: The University of New South Wales

Spatial Transcriptomics a Pathway to Dissecting Barriers to Effective Treatment in Pancreatic Cancer.
Principal Investigator: Prof Phoebe Phillips
Institute: The University of New South Wales

Repurposing FDA/TGA-approved PCSK9 inhibitor evolocumab to enhance immunotherapy outcomes in pancreatic cancer.
Principal Investigator: Prof Paul Timpson and Dr Brooke Pereira
Institute: Garvan Institute of Medical Research

2020 Collaboration Grants

Reprogramming the tumour microenvironment of pancreatic cancer to improve response to therapy
Principal Investigator: Dr Ashleigh Poh
Institute: Olivia Newton-John Cancer Research Institute

Accelerating the uptake of precision medicine in pancreatic cancer using endoscopic ultrasound biopsy.
Principal Investigator: Dr Daniel Croagh
Institute: Monash University

A sequential CRISPR approach to rationally design robust combination treatments in pancreatic cancer
Principal Investigator: Prof Frederic Hollande
Institute: The University of Melbourne

Understanding pancreatic cancer nerve invasion through investigation of the tumour microenvironment to improve patient's pain and disease treatment
Principal Investigator: Dr Katia Nones
Institute: QIMR Berghofer Medical Research Institute

Development of personalised treatment pathways for pancreatic cancer patients
Principal Investigator: Dr Sumit Sahni
Institute: The University of Sydney

2020 Early Detection Initiative Grants

Development of a novel clinical screening tool in people with diabetes and chronic pancreatitis for the early detection of pancreatic cancer.
Principal Investigator: A/Prof Andrew Metz
Institute: Epworth HealthCare

Pancreatic Cancer Early Diagnosis Group - detecting pancreatic cancer earlier before symptoms develop.
Principal Investigator: Prof Rachel Neale
Institute: QIMR Berghofer Medical Research Institute

2020 Partnered Research Projects

PRoCESS - Pancreatic Cancer Relatives Counseling and Education Support Service trial
Principal Investigator: A/Prof Vanessa Beesley
Institute: QIMR Berghofer Medical Research Institute

Development of new radioimmunotherapy agent to selectively target and kill pancreatic cancer cells
Principal Investigator: Prof Eva Bezak
Institute: University of South Australia

A novel agent for imaging and treatment of pancreatic cancer
Principal Investigator: Prof John Hooper
Institute: The University of Queensland

Surgical removal of non-metastatic pancreatic cancer – a comparison of European vs Australian practice
Principal Investigator: Prof John Zalcberg
Institute: Monash University

Next steps in harnessing a novel 'tuneable' immune checkpoint to enhance the immunogenicity of anti-pancreatic ductal adenocarcinoma
Principal Investigator: A/Prof Shane Grey
Institute: Garvan Institute of Medical Research

Developing new immunotherapies for pancreatic cancer
Principal Investigator: Dr Tatyana Chtanova
Institute: The University of New South Wales

Development of a non-invasive method of early detection for pancreatic cancer patients using nanotechnology
Principal Investigator: Dr Ying Zhu
Institute: University of New South Wales

Dual targeting of metabolic and immunological aberrations in pancreatic cancer
Principal Investigator: Dr David Herrmann
Institute: Garvan Institute of Medical Research

Starvation of pancreatic tumours by metabolically reprogramming both tumour and stromal cells
Principal Investigator: A/Prof Phoebe Phillips
Institute: The University of New South Wales

2017 Accelerator Grants

Pathway to a novel treatment for pancreatic cancer – targeting the microenvironment (stroma)
Principal Investigator: Prof Minoti Apte
Institute: University of New South Wales

Seeing is believing: Mapping and targeting the extracellular matrix in pancreatic cancer
Principal Investigator: A/Prof Paul Timpson and Dr Thomas Cox
Institute: Garvan Institute of Medical Research

2017 Innovation Grants

Therapeutic targeting of the potent metastasis suppressor, NDRG1, in pancreatic cancer
Principal Investigator: Dr Zaklina Kovacevic
Institute: University of Sydney

A novel theranostic for pancreatic cancer
Principal Investigator: Prof John Hooper
Institute: University of Queensland

Harnessing a novel ‘tunable’ immune check point to enhance the immunogenicity of anti-pancreatic ductal adenocarcinoma
Principal Investigator: A/Prof Shane Grey
Institute: Garvan Institute of Medical Research

A novel translational pipeline for the introduction of new immune-based therapies targeting localised and metastatic pancreatic ductal adenocarcinoma
Principal Investigator: Prof Brendan Jenkins
Institute: Hudson Institute of Medical Research

2016 Accelerator Grants

A novel therapeutic target in pancreatic cancer: Implications for therapy and diagnosis
Principal Investigator: Prof Marco Falasca
Institute: Curtin University

The Australian Pancreatic Cancer Organoid Biobank
Principal Investigator: Prof Sean Grimmond
Institute: University of Melbourne

2016 Innovation Grants

Therapeutically targeting a solute carrier transporter in the stroma of pancreatic cancer
Principal Investigator: A/Prof Phoebe Phillips
Institute: University of New South Wales

Development of novel agents that target P-glycoprotein resistant pancreatic cancer
Principal Investigator: Prof Des Richardson
Institute: University of Sydney

A novel therapeutic target in pancreatic cancer: Implications for therapy and diagnosis
Principal Investigator: Dr Helge Rasmussen
Institute: University of Sydney

Utilising a novel predictor to stratify patients with therapy-resistant pancreatic cancer for treatment with CHK inhibitor drugs to improve responses and outcomes
Principal Investigator: Dr Petranel Ferrao
Institute: University of Melbourne

2015 Research Funding

PanKind Surgical Workshop
Workshop Lead: Professor David Goldstein
Convenor: AGITG

2015 Accelerator Grants

The Australian Pancreatic Cancer Genome InitiativePrincipal Investigator: Prof Anthony Gill
Institute: Garvan Institute of Medical Research

A new therapy for pancreatic cancer that improves tumour microenvironment and immune cell penetration
Principal Investigator: Prof Jennifer Gamble & Prof Mathew Vadas
Institute: Centenary Institute

2015 Innovation Grants

Circulating stromal cells (pancreatic stellate cells) and tumour cells in pancreatic cancer
Principal Investigator: Prof Minoti Apte
Institute: University of New South Wales

Immunology and anti-invasive treatments for pancreatic cancer: A new therapeutic partnership
Principal Investigator: Dr Marina Pajic
Institute: Garvan Institute of Medical Research

Harnessing the power within to conquer pancreatic cancer
Principal Investigator: Dr Emily Colvin
Institute: University of Sydney

Elucidating the mechanism by which MutY-Homolog knockdown kills pancreatic cancer cells
Principal Investigator: Dr George Sharbeen
Institute: University of New South Wales

2013 Research Funding

PanKind National Research Strategy Development
Outcomes: Invest in basic and clinical research to improve outcomes for pancreatic cancer patients.

PhD Scholarship

Jeremy Humphris
Institute: Garvan Institute of Medical Research

Pankind patient and carer resources

PanKind supports people impacted by pancreatic cancer by providing relevant information, valuable resources and a connection to others affected by the disease.

We encourage you to share our resource pages with any patient, carer or community members you connect with. Our resources are provided free of charge on both soft and hard copies. You can also email info@pankind.org.au for any additional patient or support related enquiries.

Say hello to your pancreas this November

Say hello to your pancreas this November

World Pancreatic Cancer Day is a worldwide platform to speak with one voice and raise awareness together. This year again, Pankind will leverage this global campaign to raise awareness in Australia with a printed ad in The Senior, some pro-bono Out of Home, digital marketing and lighting up in purple landmark buildings around the country.

2025 Meeting Attendees

Click here to view this year's attendees.

Thank you to our sponsors