Pancreatic Cancer Early Diagnosis Group

This project focuses on detecting pancreatic cancer earlier before symptoms develop so they have a greater chance of survival.

Professor Rachel Neale is the Principal Investigator

Grant

Towards earlier diagnosis of pancreatic cancer

Award

2020/21 Early Detection Initiative

Institution

QIMR-Berghofer Medical Research Institute

Principal Investigator

Professor Rachel Neale

Time required to complete project

2 years

Project Summary

This project focuses on detecting pancreatic cancer earlier before symptoms develop so they have a greater chance of survival. General population screening is not feasible, partly due to the low incidence of pancreatic cancer in the general population, so we need to focus on people that are at a markedly higher risk of developing pancreatic cancer and create a surveillance program. The team is doing this by harnessing the power of national large-scale data linkage and modern machine learning methods to identify a cohort of patients who would benefit from surveillance. The second phase of this project focuses on reducing delays in diagnosis in general practice. Many patients and families tell stories of a distressing journey to diagnosis of pancreatic cancer. It is important that the extent, causes, and consequences of this are quantified, and that patients and general practitioners are supported to ensure prompt diagnosis. The project team has already developed a preliminary decision support tool. During this project, the tool will be further refined and made available for use by clinicians and consumers. This component of the study will be generously supported by Viatris, a global healthcare company focused on empowering people worldwide to live healthier at every stage of life.

 

Co-Investigators:
A/Prof Susan Jordan, University of Queensland
Prof Gloria Petersen, Mayo Clinic
A/Prof Joel Rhee, University of Wollongong
Prof Karen Canfell, Cancer Council NSW
A/Prof Louisa Gordon, QIMR Berghofer Medical Research Institute
Prof Benedict Devereaux, University of Queensland, Royal Brisbane and Women’s Hospital
Dr Daniel Croagh, Monash Health
Mr Paul Grogan, Cancer Council NSW
Prof John Windsor, University of Auckland, Mercy Hospital, Auckland City Hospital
A/Prof Andrew Metz, Melbourne Health
Dr Michael Caruana, Cancer Council NSW
Dr Bridie Thompson, QIMR Berghofer Medical Research Institute
Prof John Zalcberg, Monash University

Funding amount: $300,000