2017 Innovation Grants - Associate Professor Shane Grey
Professor Shane Grey
Grant
Harnessing a Novel 'Tunable' Immune Check Point to Enhance the Immunogenicity of Anti-Pancreatic Ductal Adenocarcinoma
Award
Innovation Grant 2017
Institution
The Garvan Institute of Medical Research
As a result of the genomic analysis of thousands of samples, the team at the Garvan has found a ‘volume control’ switch that they believe allows for the ‘tuning' of the immune system to be more or less aggressive. This project will test the idea that a patients T cells can be ‘tuned’ to increase the ability of their own immune system to find, infiltrate, and kill pancreatic cancer cells. Dr Grey hopes that this genetic switch can be reset in patients with pancreatic cancer to make their own immune system much better at hunting down and destroying their cancer cells.
Grant recipient A/Prof Shane Grey with Dr Marina Pajic, Dr Thomas Cox and A/Prof Paul Timpson
Research Reports
Click to download progress reporting on the outcomes of this research.